Type VII secretion system gene mutations driving global mycobacterium tuberculosis transmission revealed by whole genomic sequence

IntroductionPathogenic mycobacteria are able to transfer virulence factors across their complex cell wall using a type VII secretion system (T7SS)/early secreted antigenic target-6 of the kDa secretion system (ESX). Since the discovery of ESX loci during the Mycobacterium tuberculosis H37Rv genome p...

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Bibliographic Details
Main Authors: Jian-Jun Yang, Yuan-long Hu, Ping-yi Sun, Ling Wang, Xian-Jin Xie, Ting-Ting Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Cellular and Infection Microbiology
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Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1573643/full
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