Enhancing the Thermostability of <i>Bacillus licheniformis</i> Alkaline Protease 2709 by Computation-Based Rational Design

The alkaline protease from <i>Bacillus licheniformis</i> strain 2709 (AprE 2709) is widely used in Chinese industries but faces stability challenges under high-temperature conditions. This study employed molecular modeling and mutagenesis to identify Asn residues at positions 61, 160, an...

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Bibliographic Details
Main Authors: Yuan Yuan, Guowei Zhao, Jing Lu, Lei Wang, Yawei Shi, Jian Zhang
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Molecules
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Online Access:https://www.mdpi.com/1420-3049/30/5/1160
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