The value of metagenomic next-generation sequencing in the diagnosis of fever of unknown origin

The value of metagenomic next-generation sequencing in the diagnosis of fever of unknown origin

Abstract Fever of unknown origin (FUO) caused by infection is a disease state characterized by complex pathogens and remains a diagnostic dilemma. Metagenomic next-generation sequencing (mNGS) technology is a promising diagnostic tool for identifying pathogenic microbes of FUO caused by infection. L...

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Bibliographic Details
Main Authors: Lan Min Lai, Qing-gen Chen, Yang Liu, Rui Zhao, Mei Ling Cao, Lei Yuan
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Metagenomic next-generation sequencing
Fever of unknown origin
Infection
Sensitivity
Specificity
Online Access:https://doi.org/10.1038/s41598-025-86295-2
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https://doi.org/10.1038/s41598-025-86295-2

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