Modulation of B cell receptor activation by antibody competition

Summary: During repeated virus exposure, pre-existing antibodies can mask viral epitopes by competing with B cell receptors for antigen. Although epitope masking has the potential to steer B cell responses away from conserved epitopes and toward those that are antigenically novel, the factors that i...

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Bibliographic Details
Main Authors: Yuanyuan He, Zijian Guo, Michael D. Vahey
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Cell Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2211124725007156
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