Halloysite clay nanotubes as platforms for loading of aptamers and antisense oligonucleotides

Halloysite clay nanotubes as platforms for loading of aptamers and antisense oligonucleotides

In this study, halloysite clay nanotubes have been investigated as a platform for the encapsulation of an antisense oligonucleotide (ASO1) and a DNA aptamer (D12) with potential in the treatment of prion diseases. The loading of both molecules within halloysite cavity has been conducted by using the...

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Bibliographic Details
Main Authors: Maria Rita Caruso, Martina Maria Calvino, Giuseppe Cavallaro, Jussara Amato, Simona Marzano, Federica D'Aria, Concetta Giancola, Giuseppe Lazzara, Stefana Milioto, Bruno Pagano
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Hybrid Advances
Subjects:
Halloysite clay nanotubes
Therapeutic oligonucleotides
Hybrid nanomaterials
Colloidal stability
TGA
DLS
Online Access:http://www.sciencedirect.com/science/article/pii/S2773207X24002355
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http://www.sciencedirect.com/science/article/pii/S2773207X24002355

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