The effect of AKT inhibition in α-synuclein-dependent neurodegeneration

The effect of AKT inhibition in α-synuclein-dependent neurodegeneration

Parkinson’s disease (PD) is a progressive neurodegenerative disorder affecting millions of individuals worldwide. A hallmark of PD pathology is the accumulation of α-synuclein (α-Syn), a small protein known to support neuronal development and function. However, in PD, α-Syn cumulatively misfolds int...

Full description

Saved in:
Bibliographic Details
Main Authors: Bedri Ranxhi, Zoya R. Bangash, Zachary M. Chbihi, Sokol V. Todi, Peter A. LeWitt, Wei-Ling Tsou
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Molecular Neuroscience
Subjects:
α-synuclein
synucleinopathy
AKT
NF-κB
neurodegenerative disease
Parkinson’s disease
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2025.1524044/full
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.frontiersin.org/articles/10.3389/fnmol.2025.1524044/full

Similar Items