Central Corneal Subepithelial Haze Following Keratoplasty With Interrupted Sutures: A Novel Clinical Finding

Omar Kirat, Rawan Hawsawi, Sara AlHilali Anterior Segment Division, King Khaled Eye Specialist Hospital, Riyadh, Saudi ArabiaCorrespondence: Sara AlHilali, Anterior segment division King Khaled Eye Specialist Hospital, P.O.Box 7191, Riyadh, 11462, Saudi Arabia, Tel +966544017155, Email SaraAlHilali@...

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Main Authors: Kirat O, Hawsawi R, AlHilali S
Format: Article
Language:English
Published: Dove Medical Press 2025-01-01
Series:International Medical Case Reports Journal
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Online Access:https://www.dovepress.com/central-corneal-subepithelial-haze-following-keratoplasty-with-interru-peer-reviewed-fulltext-article-IMCRJ
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author Kirat O
Hawsawi R
AlHilali S
author_facet Kirat O
Hawsawi R
AlHilali S
author_sort Kirat O
collection DOAJ
description Omar Kirat, Rawan Hawsawi, Sara AlHilali Anterior Segment Division, King Khaled Eye Specialist Hospital, Riyadh, Saudi ArabiaCorrespondence: Sara AlHilali, Anterior segment division King Khaled Eye Specialist Hospital, P.O.Box 7191, Riyadh, 11462, Saudi Arabia, Tel +966544017155, Email SaraAlHilali@gmail.comPurpose: This study aims to describe a newly identified clinical finding of central corneal subepithelial haze following keratoplasty (both penetrating and lamellar) with interrupted sutures, and to explore its causes and management strategies.Methods: Case series.Results: The study included 7 males and 3 females, with an average age of 24.89 ± 6.57 years. Eight eyes underwent lamellar keratoplasty, and two underwent penetrating keratoplasty. Subepithelial haze appeared between 2 and 5 months postoperatively, associated with central corneal steepening. The mean BCVA improved from 0.88 ± 0.50 logMAR preoperatively to 0.51 ± 0.20 at haze documentation and 0.50 ± 0.16 after haze resolution. Selective suture removal resulted in haze resolution in 9 eyes, while delayed intervention in one case led to permanent scarring.Conclusion: Central corneal subepithelial haze following keratoplasty with interrupted sutures is linked to suture tension and central corneal steepening. Early suture adjustment or removal is essential to prevent permanent scarring. Further studies are needed to better understand this complication’s pathophysiology.Keywords: keratoplasty, sutures, subepithelial, haze
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spelling doaj-art-30b2523e4d4c4946b6bc0e75ce572d572025-01-21T16:58:06ZengDove Medical PressInternational Medical Case Reports Journal1179-142X2025-01-01Volume 1813113899384Central Corneal Subepithelial Haze Following Keratoplasty With Interrupted Sutures: A Novel Clinical FindingKirat OHawsawi RAlHilali SOmar Kirat, Rawan Hawsawi, Sara AlHilali Anterior Segment Division, King Khaled Eye Specialist Hospital, Riyadh, Saudi ArabiaCorrespondence: Sara AlHilali, Anterior segment division King Khaled Eye Specialist Hospital, P.O.Box 7191, Riyadh, 11462, Saudi Arabia, Tel +966544017155, Email SaraAlHilali@gmail.comPurpose: This study aims to describe a newly identified clinical finding of central corneal subepithelial haze following keratoplasty (both penetrating and lamellar) with interrupted sutures, and to explore its causes and management strategies.Methods: Case series.Results: The study included 7 males and 3 females, with an average age of 24.89 ± 6.57 years. Eight eyes underwent lamellar keratoplasty, and two underwent penetrating keratoplasty. Subepithelial haze appeared between 2 and 5 months postoperatively, associated with central corneal steepening. The mean BCVA improved from 0.88 ± 0.50 logMAR preoperatively to 0.51 ± 0.20 at haze documentation and 0.50 ± 0.16 after haze resolution. Selective suture removal resulted in haze resolution in 9 eyes, while delayed intervention in one case led to permanent scarring.Conclusion: Central corneal subepithelial haze following keratoplasty with interrupted sutures is linked to suture tension and central corneal steepening. Early suture adjustment or removal is essential to prevent permanent scarring. Further studies are needed to better understand this complication’s pathophysiology.Keywords: keratoplasty, sutures, subepithelial, hazehttps://www.dovepress.com/central-corneal-subepithelial-haze-following-keratoplasty-with-interru-peer-reviewed-fulltext-article-IMCRJkeratoplastysuturessubepithelialhaze
spellingShingle Kirat O
Hawsawi R
AlHilali S
Central Corneal Subepithelial Haze Following Keratoplasty With Interrupted Sutures: A Novel Clinical Finding
International Medical Case Reports Journal
keratoplasty
sutures
subepithelial
haze
title Central Corneal Subepithelial Haze Following Keratoplasty With Interrupted Sutures: A Novel Clinical Finding
title_full Central Corneal Subepithelial Haze Following Keratoplasty With Interrupted Sutures: A Novel Clinical Finding
title_fullStr Central Corneal Subepithelial Haze Following Keratoplasty With Interrupted Sutures: A Novel Clinical Finding
title_full_unstemmed Central Corneal Subepithelial Haze Following Keratoplasty With Interrupted Sutures: A Novel Clinical Finding
title_short Central Corneal Subepithelial Haze Following Keratoplasty With Interrupted Sutures: A Novel Clinical Finding
title_sort central corneal subepithelial haze following keratoplasty with interrupted sutures a novel clinical finding
topic keratoplasty
sutures
subepithelial
haze
url https://www.dovepress.com/central-corneal-subepithelial-haze-following-keratoplasty-with-interru-peer-reviewed-fulltext-article-IMCRJ
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AT hawsawir centralcornealsubepithelialhazefollowingkeratoplastywithinterruptedsuturesanovelclinicalfinding
AT alhilalis centralcornealsubepithelialhazefollowingkeratoplastywithinterruptedsuturesanovelclinicalfinding