Human cerebral organoids: Complex, versatile, and human-relevant models of neural development and brain diseases

Human cerebral organoids: Complex, versatile, and human-relevant models of neural development and brain diseases

The brain is the most complex human organ, and commonly used models, such as two-dimensional-cell cultures and animal brains, often lack the sophistication needed to accurately use in research. In this context, human cerebral organoids have emerged as valuable tools offering a more complex, versatil...

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Main Authors: Raquel Coronel, Rosa González-Sastre, Patricia Mateos-Martínez, Laura Maeso, Elena Llorente-Beneyto, Sabela Martín-Benito, Viviana S. Costa Gagosian, Leonardo Foti, Ma Carmen González-Caballero, Victoria López-Alonso, Isabel Liste
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2026-03-01
Series:Neural Regeneration Research
Subjects:
assembloids
bioengineering
challenges
disease modeling
drug screening and toxicology
human brain organoids
human pluripotent stem cells
neurodegenerative diseases
neurodevelopment
vascularization
Online Access:https://journals.lww.com/10.4103/NRR.NRR-D-24-01639
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https://journals.lww.com/10.4103/NRR.NRR-D-24-01639

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