Advances in micro-/nanorobots for cancer diagnosis and treatment: propulsion mechanisms, early detection, and cancer therapy
In recent years, medical micro-/nanorobots (MNRs) have emerged as a promising technology for diagnosing and treating malignant tumors. MNRs enable precise, targeted actions at the cellular level, addressing several limitations of conventional cancer diagnosis and treatment, such as insufficient earl...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-02-01
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| Series: | Frontiers in Chemistry |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fchem.2025.1537917/full |
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| author | Baiyang Fu Dan Luo Chao Li Yiwen Feng Wenlong Liang |
| author_facet | Baiyang Fu Dan Luo Chao Li Yiwen Feng Wenlong Liang |
| author_sort | Baiyang Fu |
| collection | DOAJ |
| description | In recent years, medical micro-/nanorobots (MNRs) have emerged as a promising technology for diagnosing and treating malignant tumors. MNRs enable precise, targeted actions at the cellular level, addressing several limitations of conventional cancer diagnosis and treatment, such as insufficient early diagnosis, nonspecific drug delivery, and chemoresistance. This review provides an in-depth discussion of the propulsion mechanisms of MNRs, including chemical fuels, external fields (light, ultrasound, magnetism), biological propulsion, and hybrid methods, highlighting their respective advantages and limitations. Additionally, we discuss novel approaches for tumor diagnosis, precision surgery, and drug delivery, emphasizing their potential clinical applications. Despite significant advancements, challenges such as biocompatibility, propulsion efficiency, and clinical translation persist. This review examines the current state of MNR applications and outlines future directions for their development, with the aim of enhancing their diagnostic and therapeutic efficacy and facilitating their integration into clinical practice. |
| format | Article |
| id | doaj-art-305660321ceb4e928b7b153690db1c88 |
| institution | Kabale University |
| issn | 2296-2646 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Chemistry |
| spelling | doaj-art-305660321ceb4e928b7b153690db1c882025-02-06T07:10:17ZengFrontiers Media S.A.Frontiers in Chemistry2296-26462025-02-011310.3389/fchem.2025.15379171537917Advances in micro-/nanorobots for cancer diagnosis and treatment: propulsion mechanisms, early detection, and cancer therapyBaiyang Fu0Dan Luo1Chao Li2Yiwen Feng3Wenlong Liang4Department of Breast Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, ChinaCollege of Automotive and Mechanical Engineering, Harbin Cambridge University, Harbin, ChinaDepartment of Rheumatology and Immunology, Daqing Oilfield General Hospital, Daqing, ChinaKey Laboratory for Micro/Nano Technology and System of Liaoning Province, Dalian University of Technology, Dalian, ChinaDepartment of Breast Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, ChinaIn recent years, medical micro-/nanorobots (MNRs) have emerged as a promising technology for diagnosing and treating malignant tumors. MNRs enable precise, targeted actions at the cellular level, addressing several limitations of conventional cancer diagnosis and treatment, such as insufficient early diagnosis, nonspecific drug delivery, and chemoresistance. This review provides an in-depth discussion of the propulsion mechanisms of MNRs, including chemical fuels, external fields (light, ultrasound, magnetism), biological propulsion, and hybrid methods, highlighting their respective advantages and limitations. Additionally, we discuss novel approaches for tumor diagnosis, precision surgery, and drug delivery, emphasizing their potential clinical applications. Despite significant advancements, challenges such as biocompatibility, propulsion efficiency, and clinical translation persist. This review examines the current state of MNR applications and outlines future directions for their development, with the aim of enhancing their diagnostic and therapeutic efficacy and facilitating their integration into clinical practice.https://www.frontiersin.org/articles/10.3389/fchem.2025.1537917/fullmicro-/nanorobotspropulsion mechanismsdrug deliverycancer diagnosistargeted therapy |
| spellingShingle | Baiyang Fu Dan Luo Chao Li Yiwen Feng Wenlong Liang Advances in micro-/nanorobots for cancer diagnosis and treatment: propulsion mechanisms, early detection, and cancer therapy Frontiers in Chemistry micro-/nanorobots propulsion mechanisms drug delivery cancer diagnosis targeted therapy |
| title | Advances in micro-/nanorobots for cancer diagnosis and treatment: propulsion mechanisms, early detection, and cancer therapy |
| title_full | Advances in micro-/nanorobots for cancer diagnosis and treatment: propulsion mechanisms, early detection, and cancer therapy |
| title_fullStr | Advances in micro-/nanorobots for cancer diagnosis and treatment: propulsion mechanisms, early detection, and cancer therapy |
| title_full_unstemmed | Advances in micro-/nanorobots for cancer diagnosis and treatment: propulsion mechanisms, early detection, and cancer therapy |
| title_short | Advances in micro-/nanorobots for cancer diagnosis and treatment: propulsion mechanisms, early detection, and cancer therapy |
| title_sort | advances in micro nanorobots for cancer diagnosis and treatment propulsion mechanisms early detection and cancer therapy |
| topic | micro-/nanorobots propulsion mechanisms drug delivery cancer diagnosis targeted therapy |
| url | https://www.frontiersin.org/articles/10.3389/fchem.2025.1537917/full |
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