Osteomodulin modulates the inflammatory responses via the interleukin-1 receptor 1/nuclear factor-κB signaling pathway in dental pulpitis

Abstract Pulpitis is a common infective oral disease in clinical situations. The regulatory mechanisms of immune defense in pulpitis are still being investigated. Osteomodulin (OMD) is a small leucine-rich proteoglycan family member distributed in bones and teeth. It is a bioactive protein that prom...

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Bibliographic Details
Main Authors: Yueyi Yang, Xuchen Hu, Meiling Jing, Xiaohan Zhu, Xiaoyu Liu, Wenduo Tan, Zhanyi Chen, Chenguang Niu, Zhengwei Huang
Format: Article
Language:English
Published: Nature Publishing Group 2025-05-01
Series:International Journal of Oral Science
Online Access:https://doi.org/10.1038/s41368-025-00369-5
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