Glycosylation of ceramide synthase 6 is required for its activity

Sphingolipids play key roles in membrane structure and cellular signaling. Ceramide synthase (CerS)-generated ceramide is implicated in cellular stress responses and induction of apoptosis. Ceramide and other sphingolipids are linked to the induction of ER stress response pathways. However, the mech...

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Bibliographic Details
Main Authors: Alexandra J. Straus, Grace Mavodza, Can E. Senkal
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227524002207
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