Corneal Biomechanical Properties in Myopic Eyes Measured by a Dynamic Scheimpflug Analyzer

Purpose. To evaluate the corneal biomechanical parameters in myopic and emmetropic eyes using Corneal Visualization Scheimpflug Technology (CorVis ST). Methods. 103 myopic and emmetropic eyes of 103 patients were examined. Corneal biomechanical parameters, axial length, and mean keratometry were mea...

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Main Authors: Jingyi Wang, Ying Li, Yumei Jin, Xue Yang, Chan Zhao, Qin Long
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2015/161869
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author Jingyi Wang
Ying Li
Yumei Jin
Xue Yang
Chan Zhao
Qin Long
author_facet Jingyi Wang
Ying Li
Yumei Jin
Xue Yang
Chan Zhao
Qin Long
author_sort Jingyi Wang
collection DOAJ
description Purpose. To evaluate the corneal biomechanical parameters in myopic and emmetropic eyes using Corneal Visualization Scheimpflug Technology (CorVis ST). Methods. 103 myopic and emmetropic eyes of 103 patients were examined. Corneal biomechanical parameters, axial length, and mean keratometry were measured using CorVis ST, IOL Master, and topography, respectively. Corneal biomechanical properties were compared within four groups. Bivariate correlation analysis was used to assess the relationship between corneal biomechanical parameters and ocular characteristics. Results. Four of ten corneal biomechanical parameters, namely, deformation amplitude (DA), first- and second-applanation time (A1-time, A2-time), and radius at highest concavity (HC radius), were significantly different within the four groups (P<0.05). In correlation analysis, DA was positively correlated with axial length (r=0.20, P=0.04); A2-time was positively correlated with spherical equivalent (SE) (r=0.24, P=0.02); HC radius was positively correlated with SE (r=0.24, P=0.02) and was negatively correlated with mean keratometry (r=-0.20, P=0.046) and axial length (r=-0.21, P=0.03). Conclusions. The corneal refraction-related biomechanical alterations were associated with ocular characteristics. Highly myopic eyes exhibited longer DA and smaller HC radius than do moderately myopic eyes; the eyes with longer axial length tend to have less corneal stiffness and are easier to deform under stress.
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spelling doaj-art-2fec36e2c2f04b3593234a0031d6f03a2025-02-03T05:50:19ZengWileyJournal of Ophthalmology2090-004X2090-00582015-01-01201510.1155/2015/161869161869Corneal Biomechanical Properties in Myopic Eyes Measured by a Dynamic Scheimpflug AnalyzerJingyi Wang0Ying Li1Yumei Jin2Xue Yang3Chan Zhao4Qin Long5Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, ChinaDepartment of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, ChinaDepartment of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, ChinaDepartment of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, ChinaDepartment of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, ChinaDepartment of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, ChinaPurpose. To evaluate the corneal biomechanical parameters in myopic and emmetropic eyes using Corneal Visualization Scheimpflug Technology (CorVis ST). Methods. 103 myopic and emmetropic eyes of 103 patients were examined. Corneal biomechanical parameters, axial length, and mean keratometry were measured using CorVis ST, IOL Master, and topography, respectively. Corneal biomechanical properties were compared within four groups. Bivariate correlation analysis was used to assess the relationship between corneal biomechanical parameters and ocular characteristics. Results. Four of ten corneal biomechanical parameters, namely, deformation amplitude (DA), first- and second-applanation time (A1-time, A2-time), and radius at highest concavity (HC radius), were significantly different within the four groups (P<0.05). In correlation analysis, DA was positively correlated with axial length (r=0.20, P=0.04); A2-time was positively correlated with spherical equivalent (SE) (r=0.24, P=0.02); HC radius was positively correlated with SE (r=0.24, P=0.02) and was negatively correlated with mean keratometry (r=-0.20, P=0.046) and axial length (r=-0.21, P=0.03). Conclusions. The corneal refraction-related biomechanical alterations were associated with ocular characteristics. Highly myopic eyes exhibited longer DA and smaller HC radius than do moderately myopic eyes; the eyes with longer axial length tend to have less corneal stiffness and are easier to deform under stress.http://dx.doi.org/10.1155/2015/161869
spellingShingle Jingyi Wang
Ying Li
Yumei Jin
Xue Yang
Chan Zhao
Qin Long
Corneal Biomechanical Properties in Myopic Eyes Measured by a Dynamic Scheimpflug Analyzer
Journal of Ophthalmology
title Corneal Biomechanical Properties in Myopic Eyes Measured by a Dynamic Scheimpflug Analyzer
title_full Corneal Biomechanical Properties in Myopic Eyes Measured by a Dynamic Scheimpflug Analyzer
title_fullStr Corneal Biomechanical Properties in Myopic Eyes Measured by a Dynamic Scheimpflug Analyzer
title_full_unstemmed Corneal Biomechanical Properties in Myopic Eyes Measured by a Dynamic Scheimpflug Analyzer
title_short Corneal Biomechanical Properties in Myopic Eyes Measured by a Dynamic Scheimpflug Analyzer
title_sort corneal biomechanical properties in myopic eyes measured by a dynamic scheimpflug analyzer
url http://dx.doi.org/10.1155/2015/161869
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