Syndrome of Inappropriate Secretion of Antidiuretic Hormone Cholestasis and Pericardial Effusion Due to Brucellosis Infection: A Case Report

Syndrome of inappropriate secretion of antidiuretic hormone (SIADH) is an extremely rare complication of infectious diseases. A rare case of brucellosis complicated by syndrome of inappropriate secretion of antidiuretic hormone (SIADH) cholestasis and pericardial involvement is reported. A 27-year-o...

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Main Authors: Ahmet Cumhur Dülger, Özgür Kemik, Aziz Sümer, Hüseyin Akdeniz, Mehmet Emin Küçükoğlu, Esra Turan Canbaz, Veyis Itik, Enver Aytemiz
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2010/850402
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author Ahmet Cumhur Dülger
Özgür Kemik
Aziz Sümer
Hüseyin Akdeniz
Mehmet Emin Küçükoğlu
Esra Turan Canbaz
Veyis Itik
Enver Aytemiz
author_facet Ahmet Cumhur Dülger
Özgür Kemik
Aziz Sümer
Hüseyin Akdeniz
Mehmet Emin Küçükoğlu
Esra Turan Canbaz
Veyis Itik
Enver Aytemiz
author_sort Ahmet Cumhur Dülger
collection DOAJ
description Syndrome of inappropriate secretion of antidiuretic hormone (SIADH) is an extremely rare complication of infectious diseases. A rare case of brucellosis complicated by syndrome of inappropriate secretion of antidiuretic hormone (SIADH) cholestasis and pericardial involvement is reported. A 27-year-old woman was admitted for fever, abdominal pain, and scleral icterus. Her medical history revealed no recent use of diuretic agents. In addition to cholestasis and elevated liver enzymes, euvolemic hyponatremia, hypouricemia, low plasma osmolality, and high urinary osmolality were also detected. Surrenal and thyroid tests were also within normal range. Echocardiography revealed minimal pericardial effusion with normal cardiac functions. The final diagnosis was SIADH due to Brucellosis. Hyponatremia, cholestasis, and pericardial disease were resolved with effective antibrucellar treatment with streptomycine and doxycycline. After completing treatment of brucellosis, there was not any more evidence of cholestasis and pericardial fluid.
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spelling doaj-art-2f9e0f998936411bab3af7e3041539d02025-02-03T06:01:02ZengWileyCase Reports in Medicine1687-96271687-96352010-01-01201010.1155/2010/850402850402Syndrome of Inappropriate Secretion of Antidiuretic Hormone Cholestasis and Pericardial Effusion Due to Brucellosis Infection: A Case ReportAhmet Cumhur Dülger0Özgür Kemik1Aziz Sümer2Hüseyin Akdeniz3Mehmet Emin Küçükoğlu4Esra Turan Canbaz5Veyis Itik6Enver Aytemiz7Department of Gastroenterology, Yüzüncü Yil University School of Medicine, 65200 Van, TurkeyDepartment of General Surgery, Yüzüncü Yil University School of Medicine, 65200 Van, TurkeyDepartment of General Surgery, Yüzüncü Yil University School of Medicine, 65200 Van, TurkeyDepartment of Radiology, Yüzüncü Yil University School of Medicine, 65200 Van, TurkeyDepartment of Gastroenterology, Yüzüncü Yil University School of Medicine, 65200 Van, TurkeyDepartment of Gastroenterology, Yüzüncü Yil University School of Medicine, 65200 Van, TurkeyDepartment of General Surgery, Yüzüncü Yil University School of Medicine, 65200 Van, TurkeyDepartment of Gastroenterology, Yüzüncü Yil University School of Medicine, 65200 Van, TurkeySyndrome of inappropriate secretion of antidiuretic hormone (SIADH) is an extremely rare complication of infectious diseases. A rare case of brucellosis complicated by syndrome of inappropriate secretion of antidiuretic hormone (SIADH) cholestasis and pericardial involvement is reported. A 27-year-old woman was admitted for fever, abdominal pain, and scleral icterus. Her medical history revealed no recent use of diuretic agents. In addition to cholestasis and elevated liver enzymes, euvolemic hyponatremia, hypouricemia, low plasma osmolality, and high urinary osmolality were also detected. Surrenal and thyroid tests were also within normal range. Echocardiography revealed minimal pericardial effusion with normal cardiac functions. The final diagnosis was SIADH due to Brucellosis. Hyponatremia, cholestasis, and pericardial disease were resolved with effective antibrucellar treatment with streptomycine and doxycycline. After completing treatment of brucellosis, there was not any more evidence of cholestasis and pericardial fluid.http://dx.doi.org/10.1155/2010/850402
spellingShingle Ahmet Cumhur Dülger
Özgür Kemik
Aziz Sümer
Hüseyin Akdeniz
Mehmet Emin Küçükoğlu
Esra Turan Canbaz
Veyis Itik
Enver Aytemiz
Syndrome of Inappropriate Secretion of Antidiuretic Hormone Cholestasis and Pericardial Effusion Due to Brucellosis Infection: A Case Report
Case Reports in Medicine
title Syndrome of Inappropriate Secretion of Antidiuretic Hormone Cholestasis and Pericardial Effusion Due to Brucellosis Infection: A Case Report
title_full Syndrome of Inappropriate Secretion of Antidiuretic Hormone Cholestasis and Pericardial Effusion Due to Brucellosis Infection: A Case Report
title_fullStr Syndrome of Inappropriate Secretion of Antidiuretic Hormone Cholestasis and Pericardial Effusion Due to Brucellosis Infection: A Case Report
title_full_unstemmed Syndrome of Inappropriate Secretion of Antidiuretic Hormone Cholestasis and Pericardial Effusion Due to Brucellosis Infection: A Case Report
title_short Syndrome of Inappropriate Secretion of Antidiuretic Hormone Cholestasis and Pericardial Effusion Due to Brucellosis Infection: A Case Report
title_sort syndrome of inappropriate secretion of antidiuretic hormone cholestasis and pericardial effusion due to brucellosis infection a case report
url http://dx.doi.org/10.1155/2010/850402
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