Organ-Preserving Surgery for Penile Carcinoma

Introduction. Penile carcinoma has traditionally been treated by either surgical amputation or radical radiotherapy, both associated with devastating anatomical, functional, and psychological impact on the patient's life. Innovative surgical techniques have focused on penile preservation in wel...

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Main Authors: Francisco E. Martins, Raul N. Rodrigues, Tomé M. Lopes
Format: Article
Language:English
Published: Wiley 2008-01-01
Series:Advances in Urology
Online Access:http://dx.doi.org/10.1155/2008/634216
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author Francisco E. Martins
Raul N. Rodrigues
Tomé M. Lopes
author_facet Francisco E. Martins
Raul N. Rodrigues
Tomé M. Lopes
author_sort Francisco E. Martins
collection DOAJ
description Introduction. Penile carcinoma has traditionally been treated by either surgical amputation or radical radiotherapy, both associated with devastating anatomical, functional, and psychological impact on the patient's life. Innovative surgical techniques have focused on penile preservation in well-selected patients to minimize physical disfigurement and consequently maximize quality of life. The objective of this article is to define the current status of these organ-preserving surgical options for penile carcinoma. Materials and Methods. An extensive review of the Pubmed literature was performed to find articles discussing only reconstructive surgery which have contributed significantly to change traditional, frequently mutilating treatments, to develop less disfiguring surgery, and to improve patients' quality of life over the last two decades. Results. Several articles were included in this analysis in which a major contribution to the change in therapy was thought to have occurred and was documented as beneficial. Some articles reported novel techniques of less-mutilating surgery involving different forms of glans reconstruction with the use of flaps or grafts. The issue of safe surgical margins was also addressed. Conclusion. The development of less-disfiguring techniques allowing phallus preservation has reduced the negative impact on functional and cosmetic outcomes of amputation without sacrificing oncological objectives in appropriately selected patients based on stage, grade, and location of the tumour. Until more prospective studies are available and solid evidence is documented, organ preservation should be offered with caution.
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spelling doaj-art-2f722287e1694210a24ca34d3bbb24dd2025-02-03T05:50:06ZengWileyAdvances in Urology1687-63691687-63772008-01-01200810.1155/2008/634216634216Organ-Preserving Surgery for Penile CarcinomaFrancisco E. Martins0Raul N. Rodrigues1Tomé M. Lopes2Departamento de Urologia, Centro Hospitalar Lisboa Norte, Hospital de Santa Maria, Universidade de Lisboa, Avenida Professor Egas Moniz, 1649-035 Lisboa, PortugalDepartamento de Urologia, Centro Hospitalar Lisboa Norte, Hospital de Santa Maria, Universidade de Lisboa, Avenida Professor Egas Moniz, 1649-035 Lisboa, PortugalDepartamento de Urologia, Centro Hospitalar Lisboa Norte, Hospital de Santa Maria, Universidade de Lisboa, Avenida Professor Egas Moniz, 1649-035 Lisboa, PortugalIntroduction. Penile carcinoma has traditionally been treated by either surgical amputation or radical radiotherapy, both associated with devastating anatomical, functional, and psychological impact on the patient's life. Innovative surgical techniques have focused on penile preservation in well-selected patients to minimize physical disfigurement and consequently maximize quality of life. The objective of this article is to define the current status of these organ-preserving surgical options for penile carcinoma. Materials and Methods. An extensive review of the Pubmed literature was performed to find articles discussing only reconstructive surgery which have contributed significantly to change traditional, frequently mutilating treatments, to develop less disfiguring surgery, and to improve patients' quality of life over the last two decades. Results. Several articles were included in this analysis in which a major contribution to the change in therapy was thought to have occurred and was documented as beneficial. Some articles reported novel techniques of less-mutilating surgery involving different forms of glans reconstruction with the use of flaps or grafts. The issue of safe surgical margins was also addressed. Conclusion. The development of less-disfiguring techniques allowing phallus preservation has reduced the negative impact on functional and cosmetic outcomes of amputation without sacrificing oncological objectives in appropriately selected patients based on stage, grade, and location of the tumour. Until more prospective studies are available and solid evidence is documented, organ preservation should be offered with caution.http://dx.doi.org/10.1155/2008/634216
spellingShingle Francisco E. Martins
Raul N. Rodrigues
Tomé M. Lopes
Organ-Preserving Surgery for Penile Carcinoma
Advances in Urology
title Organ-Preserving Surgery for Penile Carcinoma
title_full Organ-Preserving Surgery for Penile Carcinoma
title_fullStr Organ-Preserving Surgery for Penile Carcinoma
title_full_unstemmed Organ-Preserving Surgery for Penile Carcinoma
title_short Organ-Preserving Surgery for Penile Carcinoma
title_sort organ preserving surgery for penile carcinoma
url http://dx.doi.org/10.1155/2008/634216
work_keys_str_mv AT franciscoemartins organpreservingsurgeryforpenilecarcinoma
AT raulnrodrigues organpreservingsurgeryforpenilecarcinoma
AT tomemlopes organpreservingsurgeryforpenilecarcinoma