Effects of EGFR-TKIs combined with intracranial radiotherapy in EGFR-mutant non-small cell lung cancer patients with brain metastases: a retrospective multi-institutional analysis

Effects of EGFR-TKIs combined with intracranial radiotherapy in EGFR-mutant non-small cell lung cancer patients with brain metastases: a retrospective multi-institutional analysis

Abstract Background Patients with non-small cell lung cancer (NSCLC) are prone to developing brain metastases (BMs), particularly those with epidermal growth factor receptor (EGFR) mutations. In clinical practice, treatment-naïve EGFR-mutant NSCLC patients with asymptomatic BMs tend to choose EGFR-t...

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Bibliographic Details
Main Authors: Mingfeng He, Xue Wu, Li Li, Guangming Yi, Yitian Wang, Hengqiu He, Ying Ye, Ruiqin Zhou, Zaicheng Xu, Zhenzhou Yang
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Radiation Oncology
Subjects:
Non-small-cell lung cancer
Brain metastases
EGFR-TKI
Intracranial radiotherapy
Overall survival
Online Access:https://doi.org/10.1186/s13014-024-02578-4
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https://doi.org/10.1186/s13014-024-02578-4

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