6-thioguanine inhibits EV71 replication by reducing BIRC3-mediated autophagy
Abstract Background Enterovirus 71 (EV71) is one of the major causative agents of hand, foot, and mouth disease (HFMD), and can cause severe cerebral complications and even fatality in children younger than 5 years old. However, there is no specific medication for EV71 infection in clinical practice...
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Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2025-01-01
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Series: | BMC Microbiology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12866-025-03752-8 |
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