Inhibition of STING-mediated type I IFN signaling by African swine fever virus DP71L

Inhibition of STING-mediated type I IFN signaling by African swine fever virus DP71L

Abstract African swine fever virus (ASFV) is nucleocytoplasmic large DNA arbovirus and encodes many proteins involved in the interaction with host molecules to evade antiviral immune responses. Especially, evasion strategies of type I interferon (IFN-I)-mediated immune responses are crucial for earl...

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Main Authors: Lakmal Ranathunga, Sachini Abesinghe, Ji-Won Cha, Niranjan Dodantenna, Kiramage Chathuranga, Asela Weerawardhana, D. K. Haluwana, Nuwan Gamage, Jong-Soo Lee
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Veterinary Research
Subjects:
African swine fever virus (ASFV)
DP71L
SITNG
type I interferon (IFN-I)
Online Access:https://doi.org/10.1186/s13567-025-01474-3
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