Describing Point of Entry into Care and Being Lost to Program in a Cohort of HIV Positive Pregnant Women in a Large Urban Centre in Uganda

Introduction. We aim to describe the time of entry into care and factors associated with being lost to program (LTP) in pregnant women on Option B Plus in an integrated HIV and antenatal care (ANC) clinic in Uganda. Methods. We included all pregnant women enrolled into the integrated HIV-ANC clinic...

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Main Authors: Rachel Musomba, Frank Mubiru, Shadia Nakalema, Hope Mackline, Ivan Kalule, Agnes N. Kiragga, Rosalind Parkes Ratanshi, Barbara Castelnuovo
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:AIDS Research and Treatment
Online Access:http://dx.doi.org/10.1155/2017/3527563
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author Rachel Musomba
Frank Mubiru
Shadia Nakalema
Hope Mackline
Ivan Kalule
Agnes N. Kiragga
Rosalind Parkes Ratanshi
Barbara Castelnuovo
author_facet Rachel Musomba
Frank Mubiru
Shadia Nakalema
Hope Mackline
Ivan Kalule
Agnes N. Kiragga
Rosalind Parkes Ratanshi
Barbara Castelnuovo
author_sort Rachel Musomba
collection DOAJ
description Introduction. We aim to describe the time of entry into care and factors associated with being lost to program (LTP) in pregnant women on Option B Plus in an integrated HIV and antenatal care (ANC) clinic in Uganda. Methods. We included all pregnant women enrolled into the integrated HIV-ANC clinic from January 2012 to 31st July 2014, while the follow up period extended up to October 30th 2015. LTP was defined as being out of care for ≥3 months. Results. Overall 856 women were included. Only 36.4% (86/236) of the women were enrolled in the first trimester. Overall 69 (8.1%) were LTP. In the multivariate analysis older women (HR: 0.80 per five-year increase, CI: 0.64–1.0, and P=0.060) and women on ART at the time of pregnancy (0.58, CI: 0.34–0.98, and P=0.040) were more likely not to be LTP. Among women already on ART at the time of pregnancy no factor was associated with LTP. Conclusion. Our results suggest the need for interventions to enhance prompt linkage of HIV positive women to HIV services for ART initiation and for increased retention particularly in young and ART naive women.
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spelling doaj-art-2f2b25b73e6544afb44ce05427dcaf902025-02-03T01:30:59ZengWileyAIDS Research and Treatment2090-12402090-12592017-01-01201710.1155/2017/35275633527563Describing Point of Entry into Care and Being Lost to Program in a Cohort of HIV Positive Pregnant Women in a Large Urban Centre in UgandaRachel Musomba0Frank Mubiru1Shadia Nakalema2Hope Mackline3Ivan Kalule4Agnes N. Kiragga5Rosalind Parkes Ratanshi6Barbara Castelnuovo7Infectious Diseases Institute, Makerere University, Mulago Hospital, Kampala, UgandaInfectious Diseases Institute, Makerere University, Mulago Hospital, Kampala, UgandaInfectious Diseases Institute, Makerere University, Mulago Hospital, Kampala, UgandaInfectious Diseases Institute, Makerere University, Mulago Hospital, Kampala, UgandaInfectious Diseases Institute, Makerere University, Mulago Hospital, Kampala, UgandaInfectious Diseases Institute, Makerere University, Mulago Hospital, Kampala, UgandaInfectious Diseases Institute, Makerere University, Mulago Hospital, Kampala, UgandaInfectious Diseases Institute, Makerere University, Mulago Hospital, Kampala, UgandaIntroduction. We aim to describe the time of entry into care and factors associated with being lost to program (LTP) in pregnant women on Option B Plus in an integrated HIV and antenatal care (ANC) clinic in Uganda. Methods. We included all pregnant women enrolled into the integrated HIV-ANC clinic from January 2012 to 31st July 2014, while the follow up period extended up to October 30th 2015. LTP was defined as being out of care for ≥3 months. Results. Overall 856 women were included. Only 36.4% (86/236) of the women were enrolled in the first trimester. Overall 69 (8.1%) were LTP. In the multivariate analysis older women (HR: 0.80 per five-year increase, CI: 0.64–1.0, and P=0.060) and women on ART at the time of pregnancy (0.58, CI: 0.34–0.98, and P=0.040) were more likely not to be LTP. Among women already on ART at the time of pregnancy no factor was associated with LTP. Conclusion. Our results suggest the need for interventions to enhance prompt linkage of HIV positive women to HIV services for ART initiation and for increased retention particularly in young and ART naive women.http://dx.doi.org/10.1155/2017/3527563
spellingShingle Rachel Musomba
Frank Mubiru
Shadia Nakalema
Hope Mackline
Ivan Kalule
Agnes N. Kiragga
Rosalind Parkes Ratanshi
Barbara Castelnuovo
Describing Point of Entry into Care and Being Lost to Program in a Cohort of HIV Positive Pregnant Women in a Large Urban Centre in Uganda
AIDS Research and Treatment
title Describing Point of Entry into Care and Being Lost to Program in a Cohort of HIV Positive Pregnant Women in a Large Urban Centre in Uganda
title_full Describing Point of Entry into Care and Being Lost to Program in a Cohort of HIV Positive Pregnant Women in a Large Urban Centre in Uganda
title_fullStr Describing Point of Entry into Care and Being Lost to Program in a Cohort of HIV Positive Pregnant Women in a Large Urban Centre in Uganda
title_full_unstemmed Describing Point of Entry into Care and Being Lost to Program in a Cohort of HIV Positive Pregnant Women in a Large Urban Centre in Uganda
title_short Describing Point of Entry into Care and Being Lost to Program in a Cohort of HIV Positive Pregnant Women in a Large Urban Centre in Uganda
title_sort describing point of entry into care and being lost to program in a cohort of hiv positive pregnant women in a large urban centre in uganda
url http://dx.doi.org/10.1155/2017/3527563
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