LNP-enclosed NamiRNA inhibits pancreatic cancer proliferation and migration via dual pathways

Abstract Background Pancreatic cancer is a highly aggressive malignancy characterized by limited treatment options, poor prognosis, and high mortality rates. nuclear activating miRNA (NamiRNA) enhances gene expression by interacting with nuclear enhancers, offering a novel avenue for understanding g...

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Bibliographic Details
Main Authors: Chao Yu, Zhou Fang, Qingyu Xie, Zhuo Wu, Peixian Huang, Jinlong Yu, Rufu Chen
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Journal of Nanobiotechnology
Subjects:
Online Access:https://doi.org/10.1186/s12951-025-03550-4
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