SCRAPPER Regulates the Thresholds of Long-Term Potentiation/Depression, the Bidirectional Synaptic Plasticity in Hippocampal CA3-CA1 Synapses

SCRAPPER, which is an F-box protein encoded by FBXL20, regulates the frequency of the miniature excitatory synaptic current through the ubiquitination of Rab3-interacting molecule 1. Here, we recorded the induction of long-term potentiation/depression (LTP/LTD) in CA3-CA1 synapses in E3 ubiquitin li...

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Bibliographic Details
Main Authors: Hiroshi Takagi, Mitsutoshi Setou, Seiji Ito, Ikuko Yao
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Neural Plasticity
Online Access:http://dx.doi.org/10.1155/2012/352829
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