Tryptophan‐Selective Chemical Modification of Peptides by Thioether‐Mediated Sulfenylation

Tryptophan‐Selective Chemical Modification of Peptides by Thioether‐Mediated Sulfenylation

Chemical modification of biomolecules such as peptides and proteins is an important technology for the development of new functional molecules. Herein, a thioether‐mediated sulfenylation for tryptophan (Trp)‐selective chemical modification under mild metal‐free reaction conditions involving a weak a...

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Bibliographic Details
Main Authors: Hayate Shida, Akihiro Taguchi, Yuma Tokita, Yan Cui, Momoka Sakamaki, Sho Konno, Atsuhiko Taniguchi, Young Sook Yun, Yuuta Fujikawa, Hiroshi Kaneko, Hidemasa Nakaminami, Yoshio Hayashi
Format: Article
Language:English
Published: Wiley-VCH 2025-05-01
Series:ChemistryEurope
Subjects:
3‐nitro‐2‐pyridinesulfenate
amino acids
late‐stage chemical modifications
peptides
sulfenylations
Online Access:https://doi.org/10.1002/ceur.202500059
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https://doi.org/10.1002/ceur.202500059

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