T‐Cell‐Dependent Bispecific IgGs Protect Aged Mice From Lethal SARS‐CoV‐2 Infection

T‐Cell‐Dependent Bispecific IgGs Protect Aged Mice From Lethal SARS‐CoV‐2 Infection

Abstract T‐cell ageing may be a key factor in the disproportionate severity of coronavirus disease 2019 (COVID‐19) in older populations. For hospitalized COVID‐19 patients, treatment involving the use of monoclonal antibodies with the ability to neutralize SARS‐CoV‐2 usually involves the administrat...

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Bibliographic Details
Main Authors: Wenyan Fu, Wei Zhang, Zhongshuai You, Guangyao Li, Chuqi Wang, Changhai Lei, Jian Zhao, Jin Hou, Shi Hu
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Advanced Science
Subjects:
COVID19
SARS‐CoV‐2
neutralization
T cell engagers
variants of concerns
Online Access:https://doi.org/10.1002/advs.202406980
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https://doi.org/10.1002/advs.202406980

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