Sulodexide alleviates high glucose-induced cardiac microvascular endothelial cell injury in rat by activating the AMPK/SIRT1 pathway

Sulodexide alleviates high glucose-induced cardiac microvascular endothelial cell injury in rat by activating the AMPK/SIRT1 pathway

Objective To study the effect and mechanism of sulodexide (SDX) on the oxidative stress and apoptosis of cardiac microvascular endothelial cells (CMEC) in rats under high glucose (HG). Methods CMEC of rats were isolated and cultured, and randomly divided into control group, HG group and HG+SDX group...

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Bibliographic Details
Main Authors: GAO Yanli, REN Yingang, WANG Jie, KANG Li
Format: Article
Language:zho
Published: Editorial Office of Journal of Guangxi Medical University 2024-07-01
Series:Guangxi Yike Daxue xuebao
Subjects:
sulodexide
high glucose
cardiac microvascular endothelial cell
oxidative stress
apoptosis
Online Access:https://journal.gxmu.edu.cn/article/doi/10.16190/j.cnki.45-1211/r.2024.07.009
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https://journal.gxmu.edu.cn/article/doi/10.16190/j.cnki.45-1211/r.2024.07.009

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