Identification of Bexarotene as a PPARγ Antagonist with HDX
The retinoid x receptors (RXRs) are the pharmacological target of Bexarotene, an antineoplastic agent indicated for the treatment of cutaneous T cell lymphoma (CTCL). The RXRs form heterodimers with several nuclear receptors (NRs), including peroxisome proliferator-activated receptor gamma (PPARγ),...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2015-01-01
|
| Series: | PPAR Research |
| Online Access: | http://dx.doi.org/10.1155/2015/254560 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|