CDCP1-targeting ADC outperforms standard therapies in Ras-mutant pancreatic cancer
RAS mutations are found in 10%–30% of various cancers and in up to 90% of pancreatic cancers, where they are associated with aggressive phenotypes, poor prognosis, and reduced overall survival. CUB domain containing protein 1 (CDCP1), a transcriptional target of activated RAS, is implicated in these...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-09-01
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| Series: | Molecular Therapy: Oncology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2950329925000931 |
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