GRB2 regulation of essential signaling pathways in the endometrium is critical for implantation and decidualization

Abstract Over 75% of failed pregnancies involve implantation defects. Growth factor receptor-bound protein 2 (GRB2) is an adaptor protein involved in signal transduction and cell communication. Here we show that the expression of GRB2 protein is lower in endometrium of infertile women with endometri...

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Bibliographic Details
Main Authors: Dinh Nam Tran, Yeon Jeong Hwang, Keun Cheon Kim, Rong Li, Ryan M. Marquardt, Chen Chen, Steven L. Young, Bruce A. Lessey, Tae Hoon Kim, Yong-Pil Cheon, Jae-Wook Jeong
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-57173-2
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