ST-Segment Depression in Hyperventilation Indicates a False Positive Exercise Test in Patients with Mitral Valve Prolapse
Objectives. Mitral valve prolapse (MVP) is a known cause for false positive exercise test (ET). The purpose of this study was to establish additional electrocardiographic criteria to distinguish the false positive exercise results in patients with MVP. Methods. We studied 218 consecutive patients (...
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| Format: | Article |
| Language: | English |
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Wiley
2010-01-01
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| Series: | Cardiology Research and Practice |
| Online Access: | http://dx.doi.org/10.4061/2010/541781 |
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| author | Andreas P. Michaelides Charalampos I. Liakos Charalambos Antoniades Dimitrios L. Tsiachris Dimitrios Soulis Polichronis E. Dilaveris Konstantinos P. Tsioufis Christodoulos I. Stefanadis |
| author_facet | Andreas P. Michaelides Charalampos I. Liakos Charalambos Antoniades Dimitrios L. Tsiachris Dimitrios Soulis Polichronis E. Dilaveris Konstantinos P. Tsioufis Christodoulos I. Stefanadis |
| author_sort | Andreas P. Michaelides |
| collection | DOAJ |
| description | Objectives. Mitral valve prolapse (MVP) is a known cause for false positive exercise test (ET). The purpose of this study was to establish additional electrocardiographic criteria to distinguish the false positive exercise results in patients with MVP. Methods. We studied 218 consecutive patients ( years, 103 males) with MVP (according to echocardiographic study), and positive treadmill ET was performed due to multiple cardiovascular risk factors or angina-like symptoms. A coronary angiography was performed to detect coronary artery disease (CAD). Results. From 218 patients, 90 (group A) presented with normal coronary arteries according to the angiography (false positive ET) while the rest 128 (group B) presented with CAD. ST-segment depression in hyperventilation phase was present in 54 patients of group A (60%) while only in 14 patients of group B (11%), . Conclusions. Presence of ST-segment depression in hyperventilation phase favors a false positive ET in patients with MVP. |
| format | Article |
| id | doaj-art-2df7bc2d096546d8b1d80d09764936e4 |
| institution | Kabale University |
| issn | 2090-0597 |
| language | English |
| publishDate | 2010-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Cardiology Research and Practice |
| spelling | doaj-art-2df7bc2d096546d8b1d80d09764936e42025-02-03T01:04:45ZengWileyCardiology Research and Practice2090-05972010-01-01201010.4061/2010/541781541781ST-Segment Depression in Hyperventilation Indicates a False Positive Exercise Test in Patients with Mitral Valve ProlapseAndreas P. Michaelides0Charalampos I. Liakos1Charalambos Antoniades2Dimitrios L. Tsiachris3Dimitrios Soulis4Polichronis E. Dilaveris5Konstantinos P. Tsioufis6Christodoulos I. Stefanadis7Exercise Laboratory, 1st University Department of Cardiology, Athens Medical School, Hippokration Hospital, 15772 Athens, GreeceExercise Laboratory, 1st University Department of Cardiology, Athens Medical School, Hippokration Hospital, 15772 Athens, GreeceExercise Laboratory, 1st University Department of Cardiology, Athens Medical School, Hippokration Hospital, 15772 Athens, GreeceExercise Laboratory, 1st University Department of Cardiology, Athens Medical School, Hippokration Hospital, 15772 Athens, GreeceExercise Laboratory, 1st University Department of Cardiology, Athens Medical School, Hippokration Hospital, 15772 Athens, GreeceExercise Laboratory, 1st University Department of Cardiology, Athens Medical School, Hippokration Hospital, 15772 Athens, GreeceCatheterization Laboratory, 1st University Department of Cardiology, Athens Medical School, Hippokration Hospital, 15772 Athens, GreeceCatheterization Laboratory, 1st University Department of Cardiology, Athens Medical School, Hippokration Hospital, 15772 Athens, GreeceObjectives. Mitral valve prolapse (MVP) is a known cause for false positive exercise test (ET). The purpose of this study was to establish additional electrocardiographic criteria to distinguish the false positive exercise results in patients with MVP. Methods. We studied 218 consecutive patients ( years, 103 males) with MVP (according to echocardiographic study), and positive treadmill ET was performed due to multiple cardiovascular risk factors or angina-like symptoms. A coronary angiography was performed to detect coronary artery disease (CAD). Results. From 218 patients, 90 (group A) presented with normal coronary arteries according to the angiography (false positive ET) while the rest 128 (group B) presented with CAD. ST-segment depression in hyperventilation phase was present in 54 patients of group A (60%) while only in 14 patients of group B (11%), . Conclusions. Presence of ST-segment depression in hyperventilation phase favors a false positive ET in patients with MVP.http://dx.doi.org/10.4061/2010/541781 |
| spellingShingle | Andreas P. Michaelides Charalampos I. Liakos Charalambos Antoniades Dimitrios L. Tsiachris Dimitrios Soulis Polichronis E. Dilaveris Konstantinos P. Tsioufis Christodoulos I. Stefanadis ST-Segment Depression in Hyperventilation Indicates a False Positive Exercise Test in Patients with Mitral Valve Prolapse Cardiology Research and Practice |
| title | ST-Segment Depression in Hyperventilation Indicates a False Positive Exercise Test in Patients with Mitral Valve Prolapse |
| title_full | ST-Segment Depression in Hyperventilation Indicates a False Positive Exercise Test in Patients with Mitral Valve Prolapse |
| title_fullStr | ST-Segment Depression in Hyperventilation Indicates a False Positive Exercise Test in Patients with Mitral Valve Prolapse |
| title_full_unstemmed | ST-Segment Depression in Hyperventilation Indicates a False Positive Exercise Test in Patients with Mitral Valve Prolapse |
| title_short | ST-Segment Depression in Hyperventilation Indicates a False Positive Exercise Test in Patients with Mitral Valve Prolapse |
| title_sort | st segment depression in hyperventilation indicates a false positive exercise test in patients with mitral valve prolapse |
| url | http://dx.doi.org/10.4061/2010/541781 |
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