TTC36 promotes proliferation and drug resistance in hepatocellular carcinoma cells by inhibiting c-Myc degradation

TTC36 promotes proliferation and drug resistance in hepatocellular carcinoma cells by inhibiting c-Myc degradation

Abstract High c-Myc protein accumulation contributes to the proliferation, invasion, and drug resistance in multiple cancer cells, but the underlying mechanism about c-Myc accumulation remains not to be elucidated. Here, we demonstrate that TTC36 promotes c-Myc protein accumulation in hepatocellular...

Full description

Saved in:
Bibliographic Details
Main Authors: Fengling Shao, Runzhi Wang, Xinyi Li, Yanxia Hu, Zaikuan Zhang, Jing Cai, Jieru Yang, Xiaosong Feng, Suxia Ren, Zengyi Huang, Yajun Xie
Format: Article
Language:English
Published: Nature Publishing Group 2025-04-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-025-07663-4
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items