Targeting pathogenic fibroblast-like synoviocyte subsets in rheumatoid arthritis

Targeting pathogenic fibroblast-like synoviocyte subsets in rheumatoid arthritis

Abstract Fibroblast-like synoviocytes (FLSs) play a central role in RA pathogenesis and are the main cellular component in the inflamed synovium of patients with rheumatoid arthritis (RA). FLSs are emerging as promising new therapeutic targets in RA. However, fibroblasts perform many essential funct...

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Bibliographic Details
Main Authors: Hongyan Qian, Chaoqiong Deng, Shiju Chen, Xinwei Zhang, Yan He, Jingying Lan, Aodi Wang, Guixiu Shi, Yuan Liu
Format: Article
Language:English
Published: BMC 2024-05-01
Series:Arthritis Research & Therapy
Subjects:
Fibroblast-like synoviocytes
Rheumatoid arthritis
Inflammation
Immune homeostasis
Therapeutic target
Online Access:https://doi.org/10.1186/s13075-024-03343-4
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https://doi.org/10.1186/s13075-024-03343-4

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