Maternal consumption of yoghurt activating the aryl hydrocarbon receptor increases group 3 innate lymphoid cells in murine offspring

Maternal consumption of yoghurt activating the aryl hydrocarbon receptor increases group 3 innate lymphoid cells in murine offspring

ABSTRACT Indole derivatives are microbial metabolites of the tryptophan pathway involved in gut immune homeostasis. They bind to the aryl hydrocarbon receptor (AhR), thereby modulating development of intestinal group 3 innate lymphoid cells (ILC3) and subsequent interleukin-22 production. In mice, i...

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Main Authors: Grégory Pimentel, Thomas Roder, Cornelia Bär, Sandro Christensen, Zahra Sattari, Cristina Kalbermatter, Ueli von Ah, Christelle A. M. Robert, Pierre Mateo, Rémy Bruggmann, Stephanie C. Ganal-Vonarburg, Guy Vergères
Format: Article
Language:English
Published: American Society for Microbiology 2024-12-01
Series:Microbiology Spectrum
Subjects:
aryl hydrocarbon receptor
lactic acid bacteria
newborn immunity
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00393-24
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