In vitro models of microglia: a comparative study

In vitro models of microglia: a comparative study

Abstract Microglia perform key homeostatic functions to protect the central nervous system (CNS). However, in many brain disorders their protective functions are abrogated, contributing to disease progression. Therefore, studies of microglial function are critical to developing treatments for brain...

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Main Authors: Zoe Woolf, Taylor J. Stevenson, Kevin Lee, Blake Highet, Jena Macapagal Foliaki, Ramona Ratiu, Justin Rustenhoven, Jason Correia, Patrick Schweder, Peter Heppner, Maria Weinert, Natacha Coppieters, Thomas Park, Johanna Montgomery, Amy M. Smith, Michael Dragunow
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Microglia
In vitro models
Comparative analysis
iPSC-derived microglia
Human microglial clone 3 (HMC3)
Online Access:https://doi.org/10.1038/s41598-025-99867-z
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https://doi.org/10.1038/s41598-025-99867-z

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