Surgical treatment after neoadjuvant systemic therapy for HER2-positive invasive breast cancer in the Netherlands: 10-Year trends and the influence an accompanying DCIS component

Surgical treatment after neoadjuvant systemic therapy for HER2-positive invasive breast cancer in the Netherlands: 10-Year trends and the influence an accompanying DCIS component

Background: The presence of a DCIS component accompanying invasive breast cancer (IBC) is associated with a higher rate of primary mastectomy compared to IBC without DCIS. After neoadjuvant systemic therapy (NST), HER2+ IBC patients show high response rates, allowing for increasing breast-conserving...

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Main Authors: Roxanne A.W. Ploumen, Thiemo J.A. van Nijnatten, Loes F.S. Kooreman, Adri C. Voogd, Kristien B.M.I. Keymeulen, Sabine Siesling, Marjolein L. Smidt
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Breast
Subjects:
Surgical treatment
Neoadjuvant systemic therapy
Nationwide data
Invasive breast cancer
Ductal carcinoma in situ
Online Access:http://www.sciencedirect.com/science/article/pii/S0960977624001851
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http://www.sciencedirect.com/science/article/pii/S0960977624001851

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