Development of Hepatocellular Carcinoma Associated with Anabolic Androgenic Steroid Abuse in a Young Bodybuilder: A Case Report

Introduction. Many different etiological factors are involved in the development of hepatocellular carcinoma (HCC). We report the case of HCC in a 37-year-old male professional bodybuilder with extensive anabolic androgenic (AAS) steroid abuse. Case Presentation. Because of increasing epigastric and...

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Main Authors: Aline Hardt, Dirk Stippel, Margarete Odenthal, Arnulf H. Hölscher, Hans-Peter Dienes, Uta Drebber
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Case Reports in Pathology
Online Access:http://dx.doi.org/10.1155/2012/195607
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author Aline Hardt
Dirk Stippel
Margarete Odenthal
Arnulf H. Hölscher
Hans-Peter Dienes
Uta Drebber
author_facet Aline Hardt
Dirk Stippel
Margarete Odenthal
Arnulf H. Hölscher
Hans-Peter Dienes
Uta Drebber
author_sort Aline Hardt
collection DOAJ
description Introduction. Many different etiological factors are involved in the development of hepatocellular carcinoma (HCC). We report the case of HCC in a 37-year-old male professional bodybuilder with extensive anabolic androgenic (AAS) steroid abuse. Case Presentation. Because of increasing epigastric and abdominal pain, abdominal ultrasound was performed in a 37-year-old male professional bodybuilder. A hyperechoic lesion in the liver was detected in segment VI. The magnetic resonance imaging showed hepatomegaly and confirmed the lesion, which showed features of a hepatocellular adenoma (HCA). Laboratory values were inconspicuous. After laparoscopic segmentectomy the histological examination revealed HCC. Conclusion. While the development of HCA in the liver by chronic intake of AAS is well known, little is known about the association with HCC. The presented case may indicate aetiological association of chronic intake of AAS and the development of HCC.
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institution Kabale University
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language English
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record_format Article
series Case Reports in Pathology
spelling doaj-art-2c7b2233fbdc4d67b84d2eaa55ca64e92025-02-03T05:58:57ZengWileyCase Reports in Pathology2090-67812090-679X2012-01-01201210.1155/2012/195607195607Development of Hepatocellular Carcinoma Associated with Anabolic Androgenic Steroid Abuse in a Young Bodybuilder: A Case ReportAline Hardt0Dirk Stippel1Margarete Odenthal2Arnulf H. Hölscher3Hans-Peter Dienes4Uta Drebber5Department of Pathology, University Hospital of Cologne, Kerpener Straße 62, 50937 Cologne, GermanyDepartment of General Visceral and Cancer Surgery, University Hospital of Cologne, Kerpener Straße 62, 50924 Cologne, GermanyDepartment of Pathology, University Hospital of Cologne, Kerpener Straße 62, 50937 Cologne, GermanyDepartment of General Visceral and Cancer Surgery, University Hospital of Cologne, Kerpener Straße 62, 50924 Cologne, GermanyDepartment of Pathology, University Hospital of Cologne, Kerpener Straße 62, 50937 Cologne, GermanyDepartment of Pathology, University Hospital of Cologne, Kerpener Straße 62, 50937 Cologne, GermanyIntroduction. Many different etiological factors are involved in the development of hepatocellular carcinoma (HCC). We report the case of HCC in a 37-year-old male professional bodybuilder with extensive anabolic androgenic (AAS) steroid abuse. Case Presentation. Because of increasing epigastric and abdominal pain, abdominal ultrasound was performed in a 37-year-old male professional bodybuilder. A hyperechoic lesion in the liver was detected in segment VI. The magnetic resonance imaging showed hepatomegaly and confirmed the lesion, which showed features of a hepatocellular adenoma (HCA). Laboratory values were inconspicuous. After laparoscopic segmentectomy the histological examination revealed HCC. Conclusion. While the development of HCA in the liver by chronic intake of AAS is well known, little is known about the association with HCC. The presented case may indicate aetiological association of chronic intake of AAS and the development of HCC.http://dx.doi.org/10.1155/2012/195607
spellingShingle Aline Hardt
Dirk Stippel
Margarete Odenthal
Arnulf H. Hölscher
Hans-Peter Dienes
Uta Drebber
Development of Hepatocellular Carcinoma Associated with Anabolic Androgenic Steroid Abuse in a Young Bodybuilder: A Case Report
Case Reports in Pathology
title Development of Hepatocellular Carcinoma Associated with Anabolic Androgenic Steroid Abuse in a Young Bodybuilder: A Case Report
title_full Development of Hepatocellular Carcinoma Associated with Anabolic Androgenic Steroid Abuse in a Young Bodybuilder: A Case Report
title_fullStr Development of Hepatocellular Carcinoma Associated with Anabolic Androgenic Steroid Abuse in a Young Bodybuilder: A Case Report
title_full_unstemmed Development of Hepatocellular Carcinoma Associated with Anabolic Androgenic Steroid Abuse in a Young Bodybuilder: A Case Report
title_short Development of Hepatocellular Carcinoma Associated with Anabolic Androgenic Steroid Abuse in a Young Bodybuilder: A Case Report
title_sort development of hepatocellular carcinoma associated with anabolic androgenic steroid abuse in a young bodybuilder a case report
url http://dx.doi.org/10.1155/2012/195607
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