Multipotent Effect of Clozapine on Lipopolysaccharide-Induced Acetylcholinesterase, Cyclooxygenase-2,5-Lipoxygenase, and Caspase-3: In Vivo and Molecular Modeling Studies

Dual inhibition of cyclooxygenase-2 (COX-2) and lipoxygenase (LOX) is a recognized strategy for enhanced anti-inflammatory effects in small molecules, offering potential therapeutic benefits for individuals at risk of dementia, particularly those with neurodegenerative diseases, common cancers, and...

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Bibliographic Details
Main Authors: Minhajul Arfeen, Devendra Kumar Dhaked, Vasudevan Mani
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/30/2/266
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