Predicting cellular adaptation proteins dependent on eIF2α regulation under stress conditions: Physiological and pathophysiological implications in neuronal function

Predicting cellular adaptation proteins dependent on eIF2α regulation under stress conditions: Physiological and pathophysiological implications in neuronal function

Understanding the intricate mechanisms governing gene expression regulation is crucial for deciphering neuronal responses to cellular stress at both the physiological (i.e., synaptogenesis) and pathophysiological (i.e., neurodegenerative diseases) levels. These rapid adaptive changes depend on the t...

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Bibliographic Details
Main Authors: Víctor Herrera-Fernández, Hugo Fanlo-Ucar, Patrick Gohl, Melisa Ece Zeylan, Simge Senyuz, Ozlem Keskin, Attila Gursoy, Rubén Vicente, Baldo Oliva, Francisco J. Muñoz
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
eIF2α
Integrated stress response
Cell translation
Synaptoplasticity
Neurodegeneration
SLC30A4
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037025002740
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