Surprising features of nuclear receptor interaction networks revealed by live-cell single-molecule imaging

Surprising features of nuclear receptor interaction networks revealed by live-cell single-molecule imaging

Type II nuclear receptors (T2NRs) require heterodimerization with a common partner, the retinoid X receptor (RXR), to bind cognate DNA recognition sites in chromatin. Based on previous biochemical and overexpression studies, binding of T2NRs to chromatin is proposed to be regulated by competition fo...

Full description

Saved in:
Bibliographic Details
Main Authors: Liza Dahal, Thomas GW Graham, Gina M Dailey, Alec Heckert, Robert Tjian, Xavier Darzacq
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-01-01
Series:eLife
Subjects:
single-molecule tracking
nuclear receptors
transcription factors
gene regulatory networks
molecular biophysics
protein-protein interactions
Online Access:https://elifesciences.org/articles/92979
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://elifesciences.org/articles/92979

Similar Items