Knockdown of the long noncoding RNA VSIG2-1:1 promotes the angiogenic ability of human pulmonary microvascular endothelial cells by activating the VEGF/PI3K/AKT pathway

Knockdown of the long noncoding RNA VSIG2-1:1 promotes the angiogenic ability of human pulmonary microvascular endothelial cells by activating the VEGF/PI3K/AKT pathway

Abstract Background Abnormal pulmonary vascular development poses significant clinical challenges for infants with bronchopulmonary dysplasia (BPD). Although numerous factors have been suggested to control the development of pulmonary blood vessels, the mechanisms underlying the role of long noncodi...

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Bibliographic Details
Main Authors: Xiaoya Hu, Yihui Zheng, Mingchu Fang, Zhongjie Liang, Chao Wen, Jing Lin, Zhenlang Lin, Shangqin Chen
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Respiratory Research
Subjects:
Long noncoding RNA
Bronchopulmonary dysplasia
Pulmonary microvascular endothelial cells
Angiogenesis
VEGF/PI3K/AKT pathway
Online Access:https://doi.org/10.1186/s12931-024-03039-y
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https://doi.org/10.1186/s12931-024-03039-y

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