New derivatives of benzhydroxamic acid with nematocidal activity against Haemonchus contortus and Caenorhabditis elegans

New derivatives of benzhydroxamic acid with nematocidal activity against Haemonchus contortus and Caenorhabditis elegans

Parasitic nematodes cause a wide range of diseases in animals, including humans. However, the efficacy of existing anthelmintic drugs, commonly used to treat these infections, is waning due to the increasing prevalence of drug resistance in nematode populations. This growing challenge underscores th...

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Main Authors: Josef Krátký, Markéta Zajíčková, Aya C. Taki, Oliver Michel, Petra Matoušková, Ivan Vokřál, Karolína Štěrbová, Ondřej Vosála, Beate Lungerich, Thomas Kurz, Robin B. Gasser, Karel Harant, Lenka Skálová
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:International Journal for Parasitology: Drugs and Drug Resistance
Subjects:
Drug development
Drug resistance
Nematodes
New anthelmintics
Online Access:http://www.sciencedirect.com/science/article/pii/S2211320725000223
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