Predictive value of epicardial fat thickness for left ventricular reverse remodeling after radiofrequency ablation in atrial fibrillation patients with left ventricular hypertrophy

[Objective] To investigate the predictive value of epicardial fat thickness (EFT) for left ventricular reverse remodeling after radiofrequency ablation in patients with left ventricular hypertrophy. [Methods] A total of 50 patients with atrial fibrillation admitted to Shanxi Bethune Hospital from Ju...

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Main Authors: Ke Hu, Wenhui Wang, Junping Zhen, Chunsong Kang
Format: Article
Language:zho
Published: Editorial Office of International Journal of Geriatrics 2025-01-01
Series:Guoji laonian yixue zazhi
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Online Access:http://gwll.publish.founderss.cn/thesisDetails#10.3969/j.issn.1674-7593.2025.01.002&lang=en
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author Ke Hu
Wenhui Wang
Junping Zhen
Chunsong Kang
author_facet Ke Hu
Wenhui Wang
Junping Zhen
Chunsong Kang
author_sort Ke Hu
collection DOAJ
description [Objective] To investigate the predictive value of epicardial fat thickness (EFT) for left ventricular reverse remodeling after radiofrequency ablation in patients with left ventricular hypertrophy. [Methods] A total of 50 patients with atrial fibrillation admitted to Shanxi Bethune Hospital from June 2021 to September 2023 were retrospectively collected.The clinical data of the patients were collected by electronic medical records.EFT was examined by echocardiography.The patients were divided into groups according to whether reverse remodeling was achieved.Univariate and multivariate logistic regression models were used to analyze the factors of postoperative left ventricular reverse remodeling.ROC curve was used to analyze the predictive value of EFT. [Results] A total of 28 patients who did not achieve reverse remodeling were included in the control group, and 22 patients who achieved reverse remodeling were included in the reverse remodeling group.There were significant differences in age, atrial fibrillation classification, duration of atrial fibrillation, left atrial diameter (LAD), left ventricular end-diastolic diameter, left ventricular end-diastolic diameter index (LVEDI), neutrophil to lymphocyte ratio (NLR), high-sensitivity C-reactive protein (hsCRP), platelet distribution width(PDW), red cell distribution width, fibrinogen to albumin ratio (FAR) and EFT between the two groups (P<0.05).Multivariate logistic regression analysis showed that EFT, LAD, LVEDI, NLR, hsCRP, PDW and FAR were independent factors for left ventricular reverse remodeling(P<0.05).The cut-off value of EFT for predicting postoperative left ventricular reverse remodeling was 0.848, sensitivity was 95.5%, specificity was 89.3%, and AUC was 0.937 (95% CI: 0.868-0.983). [Conclusion] EFT has a high predictive value for postoperative left ventricular reverse remodeling in patients with left ventricular hypertrophy.
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spelling doaj-art-2bebf5ec5f8b4a679d5ecda29596ba3c2025-01-21T02:59:39ZzhoEditorial Office of International Journal of GeriatricsGuoji laonian yixue zazhi1674-75932025-01-014615910.3969/j.issn.1674-7593.2025.01.002Predictive value of epicardial fat thickness for left ventricular reverse remodeling after radiofrequency ablation in atrial fibrillation patients with left ventricular hypertrophyKe Hu0Wenhui Wang1Junping Zhen2Chunsong Kang3Shanxi Medical University, Taiyuan 030607Shanxi Medical University, Taiyuan 030607Shanxi Medical University, Taiyuan 030607Shanxi Bethune Hospital, Taiyuan 030001[Objective] To investigate the predictive value of epicardial fat thickness (EFT) for left ventricular reverse remodeling after radiofrequency ablation in patients with left ventricular hypertrophy. [Methods] A total of 50 patients with atrial fibrillation admitted to Shanxi Bethune Hospital from June 2021 to September 2023 were retrospectively collected.The clinical data of the patients were collected by electronic medical records.EFT was examined by echocardiography.The patients were divided into groups according to whether reverse remodeling was achieved.Univariate and multivariate logistic regression models were used to analyze the factors of postoperative left ventricular reverse remodeling.ROC curve was used to analyze the predictive value of EFT. [Results] A total of 28 patients who did not achieve reverse remodeling were included in the control group, and 22 patients who achieved reverse remodeling were included in the reverse remodeling group.There were significant differences in age, atrial fibrillation classification, duration of atrial fibrillation, left atrial diameter (LAD), left ventricular end-diastolic diameter, left ventricular end-diastolic diameter index (LVEDI), neutrophil to lymphocyte ratio (NLR), high-sensitivity C-reactive protein (hsCRP), platelet distribution width(PDW), red cell distribution width, fibrinogen to albumin ratio (FAR) and EFT between the two groups (P<0.05).Multivariate logistic regression analysis showed that EFT, LAD, LVEDI, NLR, hsCRP, PDW and FAR were independent factors for left ventricular reverse remodeling(P<0.05).The cut-off value of EFT for predicting postoperative left ventricular reverse remodeling was 0.848, sensitivity was 95.5%, specificity was 89.3%, and AUC was 0.937 (95% CI: 0.868-0.983). [Conclusion] EFT has a high predictive value for postoperative left ventricular reverse remodeling in patients with left ventricular hypertrophy.http://gwll.publish.founderss.cn/thesisDetails#10.3969/j.issn.1674-7593.2025.01.002&lang=enatrial fibrillationleft ventricular hypertrophyradiofrequency ablationleft ventricular reverse remodelingepicardial fat thickness
spellingShingle Ke Hu
Wenhui Wang
Junping Zhen
Chunsong Kang
Predictive value of epicardial fat thickness for left ventricular reverse remodeling after radiofrequency ablation in atrial fibrillation patients with left ventricular hypertrophy
Guoji laonian yixue zazhi
atrial fibrillation
left ventricular hypertrophy
radiofrequency ablation
left ventricular reverse remodeling
epicardial fat thickness
title Predictive value of epicardial fat thickness for left ventricular reverse remodeling after radiofrequency ablation in atrial fibrillation patients with left ventricular hypertrophy
title_full Predictive value of epicardial fat thickness for left ventricular reverse remodeling after radiofrequency ablation in atrial fibrillation patients with left ventricular hypertrophy
title_fullStr Predictive value of epicardial fat thickness for left ventricular reverse remodeling after radiofrequency ablation in atrial fibrillation patients with left ventricular hypertrophy
title_full_unstemmed Predictive value of epicardial fat thickness for left ventricular reverse remodeling after radiofrequency ablation in atrial fibrillation patients with left ventricular hypertrophy
title_short Predictive value of epicardial fat thickness for left ventricular reverse remodeling after radiofrequency ablation in atrial fibrillation patients with left ventricular hypertrophy
title_sort predictive value of epicardial fat thickness for left ventricular reverse remodeling after radiofrequency ablation in atrial fibrillation patients with left ventricular hypertrophy
topic atrial fibrillation
left ventricular hypertrophy
radiofrequency ablation
left ventricular reverse remodeling
epicardial fat thickness
url http://gwll.publish.founderss.cn/thesisDetails#10.3969/j.issn.1674-7593.2025.01.002&lang=en
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AT junpingzhen predictivevalueofepicardialfatthicknessforleftventricularreverseremodelingafterradiofrequencyablationinatrialfibrillationpatientswithleftventricularhypertrophy
AT chunsongkang predictivevalueofepicardialfatthicknessforleftventricularreverseremodelingafterradiofrequencyablationinatrialfibrillationpatientswithleftventricularhypertrophy