Impaired liver function: effect on paclitaxel toxicity, dose modifications and overall survival

Impaired liver function: effect on paclitaxel toxicity, dose modifications and overall survival

Abstract Background The anticancer drug paclitaxel is primarily metabolized in the liver. Previous studies have indicated a correlation between impaired liver function and paclitaxel toxicity, which may indicate dose reduction. Since the evidence is limited, the aim of this study was to investigate...

Full description

Saved in:
Bibliographic Details
Main Authors: Marieke Schmidt, Robin Vernooij, Merel van Nuland, Erin Smeijsters, Lot Devriese, Nadia Haj Mohammad, Thom Hermens, Julian Stammers, Christina Swart, Toine Egberts, Saskia Haitjema, Laureen Lammers
Format: Article
Language:English
Published: BMC 2024-12-01
Series:BMC Cancer
Subjects:
Paclitaxel toxicity
Impaired liver function
paclitaxel dose modifications
Online Access:https://doi.org/10.1186/s12885-024-13330-2
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1186/s12885-024-13330-2

Similar Items