Activation of Endoplasmic Reticulum-Localized Metabotropic Glutamate Receptor 5 (mGlu<sub>5</sub>) Triggers Calcium Release Distinct from Cell Surface Counterparts in Striatal Neurons

Metabotropic glutamate receptor 5 (mGlu<sub>5</sub>) plays a fundamental role in synaptic plasticity, potentially serving as a therapeutic target for various neurodevelopmental and psychiatric disorders. Previously, we have shown that mGlu<sub>5</sub> can also signal from int...

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Bibliographic Details
Main Authors: Yuh-Jiin I. Jong, Steven K. Harmon, Karen L. O’Malley
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Biomolecules
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Online Access:https://www.mdpi.com/2218-273X/15/4/552
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