Screening and mechanistic study of natural compounds that enhance T cell anti-tumor effects post-heat treatment

Screening and mechanistic study of natural compounds that enhance T cell anti-tumor effects post-heat treatment

IntroductionFollowing the approval of Chimeric Antigen Receptor T-cell Immunotherapy(CAR-T) in multiple countries, the Food and Drug Administration (FDA) approved tumor-infiltrating lymphocytes (TILs) and T-cell receptor-engineered T cells (TCR-T) treatments this year. The utilization of adoptive im...

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Bibliographic Details
Main Authors: Zhaoyi Wang, Zhongqi Diao, Yiyan Zhang, Jiangying Liu, Yeshan Li, Zijin Sun, Huimin Zhen, Haojia Wang, Siyun Yang, Tieshan Wang, Lei Ni
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Immunology
Subjects:
adoptive cell therapy
Chinese medicine
temperature
proteomics
untargeted metabolomics
enhance immunity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1537398/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1537398/full

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