Time-course of muscle fatigue development during intense exercise in hypoxia and normoxia

Abstract This study is the first to determine how hypoxia affects human muscle fatigue kinetics and metabolic perturbations during intense dynamic exercise. Using randomized, single-blinded crossover designs, three trials of two-legged knee extensions were performed under hypoxic (HYP, FiO₂ 0.135) a...

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Bibliographic Details
Main Authors: Jacob Bejder, Jonathan Graae, Jakob Boye Andersen, Ricardo Augusto Barbieri, Eduardo Zapaterra Campos, Jens Bangsbo, Lars Nybo, Nikolai Baastrup Nordsborg
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-98762-x
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