Glyceraldehyde 3-Phosphate Dehydrogenase and Galectin from <i>Dirofilaria immitis</i> Excretory/Secretory Antigens Activate Proangiogenic Pathway in In Vitro Vascular Endothelial Cell Model

Glyceraldehyde 3-Phosphate Dehydrogenase and Galectin from <i>Dirofilaria immitis</i> Excretory/Secretory Antigens Activate Proangiogenic Pathway in In Vitro Vascular Endothelial Cell Model

Heartworm disease is caused by <i>Dirofilaria immitis</i>, which mainly affects canids and felids. Adult <i>D. immitis</i> worms are located between the heart’s right ventricle and the pulmonary artery. These parasites produce an inflammatory and hypoxic process in the vascul...

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Bibliographic Details
Main Authors: Manuel Collado-Cuadrado, Alfonso Balmori-de la Puente, Iván Rodríguez-Escolar, Elena Infante González-Mohino, Claudia Alarcón-Torrecillas, Miguel Pericacho, Rodrigo Morchón
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Animals
Subjects:
angiogenesis
<i>Dirofilaria immitis</i> excretory/secretory antigens
cellular processes
galectin
glyceraldehyde 3-phosphate dehydrogenase
Online Access:https://www.mdpi.com/2076-2615/15/7/964
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