DA-DRD5 signaling reprograms B cells to promote CD8+ T cell-mediated antitumor immunity

DA-DRD5 signaling reprograms B cells to promote CD8+ T cell-mediated antitumor immunity

Summary: Neuronal signals have emerged as pivotal regulators of B cells that regulate antitumor immunity and tumor progression. However, the functional relevance and mechanistic basis of the effects of the neurotransmitter dopamine (DA) on tumor immunity remain elusive. Here, we discovered that plas...

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Main Authors: Yuqing Wu, Lei Zhu, Sheng Li, Lu Liu, Yaman Wang, Yongbing Yang, Yuan Mu, Qiuying Zhu, Yuying Jiang, Chunyan Wu, Peiwen Xi, Chunmei Ma, Lijun Liang, Min Gao, Yingchao Hu, Qiang Ding, Shiyang Pan
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Cell Reports
Subjects:
CP: Immunology
CP: Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124725001354
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http://www.sciencedirect.com/science/article/pii/S2211124725001354

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