The Pathophysiological Relationship Between Migraine and SARS-CoV-2 Infection: A Comprehensive Literature Review
People with migraine, and individuals with other neurological conditions, have suffered in multiple aspects during the COVID-19 pandemic. This paper will discuss the factors that impacted the neurology department. The emergence of severe acute respiratory syndrome coronavirus 2 in late 2019 has gen...
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| Format: | Article |
| Language: | English |
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European Medical Journal
2022-12-01
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| Series: | European Medical Journal |
| Online Access: | https://www.emjreviews.com/flagship-journal/article/the-pathophysiological-relationship-between-migraine-and-sars-cov-2-infection-a-comprehensive-literature-review-j190422/ |
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| author | Noor Elkurwi Qabas Elkurwi |
| author_facet | Noor Elkurwi Qabas Elkurwi |
| author_sort | Noor Elkurwi |
| collection | DOAJ |
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People with migraine, and individuals with other neurological conditions, have suffered in multiple aspects during the COVID-19 pandemic. This paper will discuss the factors that impacted the neurology department. The emergence of severe acute respiratory syndrome coronavirus 2 in late 2019 has generated new challenges in healthcare systems across the globe. Similar to the fields of pulmonology and cardiology that saw an increase in research, the neurology department was in search of possible relationships between COVID-19 and other medical conditions. Research on the possible common pathophysiological mechanism between COVID-19 and migraine is currently being studied. The most recent hypothesis suggests the following: migraine is caused by an increased release of calcitonin gene-related peptide from the trigeminal ganglion, which will cause an increase in nitric oxide and IL-1β, resulting in vasodilation and inducing hyperalgesia. COVID-19 causes an increase in nod-like receptor protein 3, which causes the production of IL-1β and again induces an inflammatory response. This review article looks at the mechanisms of migraine and COVID-19, and tries to link a common pathophysiological pathway between the two. This report also serves as a gateway for further research regarding possible management that could potentially target both of these mechanisms. |
| format | Article |
| id | doaj-art-2a4418eff49c45a3a3751eb6ae0bf619 |
| institution | Kabale University |
| issn | 2397-6764 |
| language | English |
| publishDate | 2022-12-01 |
| publisher | European Medical Journal |
| record_format | Article |
| series | European Medical Journal |
| spelling | doaj-art-2a4418eff49c45a3a3751eb6ae0bf6192025-01-23T10:26:58ZengEuropean Medical JournalEuropean Medical Journal2397-67642022-12-01465510.33590/emj/10054250The Pathophysiological Relationship Between Migraine and SARS-CoV-2 Infection: A Comprehensive Literature ReviewNoor Elkurwi0Qabas Elkurwi1Department of Neurology, Stroke and Neurorehabilitation, Barlicki Hospital, Medical University of Łódź, PolandDepartment of Neurology, Stroke and Neurorehabilitation, Barlicki Hospital, Medical University of Łódź, Poland People with migraine, and individuals with other neurological conditions, have suffered in multiple aspects during the COVID-19 pandemic. This paper will discuss the factors that impacted the neurology department. The emergence of severe acute respiratory syndrome coronavirus 2 in late 2019 has generated new challenges in healthcare systems across the globe. Similar to the fields of pulmonology and cardiology that saw an increase in research, the neurology department was in search of possible relationships between COVID-19 and other medical conditions. Research on the possible common pathophysiological mechanism between COVID-19 and migraine is currently being studied. The most recent hypothesis suggests the following: migraine is caused by an increased release of calcitonin gene-related peptide from the trigeminal ganglion, which will cause an increase in nitric oxide and IL-1β, resulting in vasodilation and inducing hyperalgesia. COVID-19 causes an increase in nod-like receptor protein 3, which causes the production of IL-1β and again induces an inflammatory response. This review article looks at the mechanisms of migraine and COVID-19, and tries to link a common pathophysiological pathway between the two. This report also serves as a gateway for further research regarding possible management that could potentially target both of these mechanisms.https://www.emjreviews.com/flagship-journal/article/the-pathophysiological-relationship-between-migraine-and-sars-cov-2-infection-a-comprehensive-literature-review-j190422/ |
| spellingShingle | Noor Elkurwi Qabas Elkurwi The Pathophysiological Relationship Between Migraine and SARS-CoV-2 Infection: A Comprehensive Literature Review European Medical Journal |
| title | The Pathophysiological Relationship Between Migraine and SARS-CoV-2 Infection: A Comprehensive Literature Review |
| title_full | The Pathophysiological Relationship Between Migraine and SARS-CoV-2 Infection: A Comprehensive Literature Review |
| title_fullStr | The Pathophysiological Relationship Between Migraine and SARS-CoV-2 Infection: A Comprehensive Literature Review |
| title_full_unstemmed | The Pathophysiological Relationship Between Migraine and SARS-CoV-2 Infection: A Comprehensive Literature Review |
| title_short | The Pathophysiological Relationship Between Migraine and SARS-CoV-2 Infection: A Comprehensive Literature Review |
| title_sort | pathophysiological relationship between migraine and sars cov 2 infection a comprehensive literature review |
| url | https://www.emjreviews.com/flagship-journal/article/the-pathophysiological-relationship-between-migraine-and-sars-cov-2-infection-a-comprehensive-literature-review-j190422/ |
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