Optimized scaffold-free human 3D adipose tissue organoid culture for obesity and disease modeling

Obesity and type 2 diabetes (T2D) are strongly linked to abnormal adipocyte metabolism and adipose tissue (AT) dysfunction. However, existing adipose tissue models have limitations, particularly in the stable culture of fat cells that maintain physiologically relevant phenotypes, hindering a deeper...

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Bibliographic Details
Main Authors: Rafael Dariolli, Raphael Nir, Tova Mushlam, Glauco R. Souza, Stephen R. Farmer, Miguel L Batista, Jr.
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:SLAS Discovery
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Online Access:http://www.sciencedirect.com/science/article/pii/S2472555225000115
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