Gut opportunistic pathogens contribute to high-altitude pulmonary edema by elevating lysophosphatidylcholines and inducing inflammation

Gut opportunistic pathogens contribute to high-altitude pulmonary edema by elevating lysophosphatidylcholines and inducing inflammation

ABSTRACT Gut microbiota have been found to promote hypoxia-induced intestinal injury. However, the role of gut microbiota in high-altitude pulmonary edema (HAPE), the preventive effect of synbiotic on HAPE, and the mechanisms by which they might work remain unknown. In this study, we aimed to invest...

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Bibliographic Details
Main Authors: Xianduo Sun, Gaosheng Hu, Yuting Li, Wenjing Li, Yong Wang, Hui Yan, Guoqing Long, Long Zhao, Anhua Wang, Jingming Jia
Format: Article
Language:English
Published: American Society for Microbiology 2025-07-01
Series:Microbiology Spectrum
Subjects:
high-altitude pulmonary edema
gut microbiota
lysophosphatidylcholines
inflammation
Online Access:https://journals.asm.org/doi/10.1128/spectrum.03057-24
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