IFNλ is a potent anti‐influenza therapeutic without the inflammatory side effects of IFNα treatment

Abstract Influenza A virus (IAV)‐induced severe disease is characterized by infected lung epithelia, robust inflammatory responses and acute lung injury. Since type I interferon (IFNαβ) and type III interferon (IFNλ) are potent antiviral cytokines with immunomodulatory potential, we assessed their e...

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Bibliographic Details
Main Authors: Sophia Davidson, Teresa M McCabe, Stefania Crotta, Hans Henrik Gad, Edith M Hessel, Soren Beinke, Rune Hartmann, Andreas Wack
Format: Article
Language:English
Published: Springer Nature 2016-08-01
Series:EMBO Molecular Medicine
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Online Access:https://doi.org/10.15252/emmm.201606413
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