Micronized purified flavonoid fraction (daflon) improves sexual function by modulating NF-kB /NO/cGMP and steroidogenic signaling in cisplatin-treated male Wistar rats
Cisplatin is known to induce sexual dysfunction by suppressing testosterone levels. It also upregulates nuclear factor-kappa B (NF-kB), which mediates nitric oxide (NO)-dependent endothelial dysfunction. This study evaluated the effects of daflon, a micronized purified flavonoid fraction that contai...
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| Main Authors: | Akhigbe RE, Akhigbe TM, Adegbola CA |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-09-01
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| Series: | Biochemistry and Biophysics Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405580825002316 |
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